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020 _a9780691138916
040 _aICTS-TIFR
050 _aQH505 .B455
100 _aBialek, William S.
245 _aBiophysics : searching for principles
260 _bPrinceton University Press,
_aPrinceton, NJ:
_cc2012
300 _a656 p.
520 _aInteractions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology—from the discovery of DNA’s structure to imaging of the human brain—have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles—the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems.
856 _uhttp://www.princeton.edu/~wbialek/biophysbook.html?_ga=2.78179284.1327725280.1688380705-317263596.1684301053
_ySupplementary Materials
856 _uhttps://press.princeton.edu/textbooks/illustrations/bialek
_yIllustration Package
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_cBK
999 _c32905
_d32905